Meconium ileus is most commonly associated with which disease?

Meconium ileus is a condition characterized by the obstruction of the intestines due to thick, sticky meconium, and it is most commonly associated with cystic fibrosis. Cystic fibrosis is a genetic disorder that affects the exocrine glands, leading to the production of abnormally thick secretions, which can obstruct various organs, including the intestines. In the case of meconium ileus, the thickened meconium can block the intestines, leading to symptoms such as abdominal distension and failure to pass meconium.

Early recognition and treatment of meconium ileus are critical, as it can lead to serious complications if not addressed promptly. Cystic fibrosis not only predisposes infants to gastrointestinal obstructions like meconium ileus but also often leads to respiratory complications due to thick mucus production in the lungs. Thus, understanding the association between cystic fibrosis and meconium ileus helps healthcare providers manage and anticipate potential complications in affected newborns.