What condition can G6PD deficiency cause in newborns?

G6PD (Glucose-6-Phosphate Dehydrogenase) deficiency is an inherited enzyme deficiency that can lead to hemolytic anemia in newborns. This condition occurs when there is a lack of the enzyme G6PD, which plays a crucial role in protecting red blood cells from oxidative stress. When newborns with G6PD deficiency are exposed to certain triggers, such as infections, certain drugs, or certain foods, their red blood cells can become damaged and undergo hemolysis, or breakdown.

This breakdown of red blood cells leads to hemolytic anemia, characterized by symptoms such as jaundice, pallor, and fatigue. The newborn's kidney function can also be affected due to the increased breakdown products of hemoglobin. Understanding the implications of G6PD deficiency is crucial for neonatal care, ensuring that affected infants receive appropriate monitoring and management to prevent complications related to hemolytic anemia.