What is the primary concern with early skull bone fusion in neonates?

The primary concern with early skull bone fusion in neonates, known as craniosynostosis, is brain growth interference. In neonates, the skull bones are not fused and remain flexible to accommodate the rapid growth of the brain during the first years of life. When one or more sutures of the skull fuse prematurely, it restricts the normal expansion of the skull as the brain grows, potentially leading to increased intracranial pressure, developmental delays, and other neurological issues.

The brain requires adequate space to develop, and if the skull does not allow for this growth, it can have significant long-term effects on cognitive and physical development. Addressing craniosynostosis often involves surgical intervention to correct the shape of the skull and provide the necessary space for the brain to grow and function properly.

The other concerns, such as vision problems, hearing loss, or respiratory issues, may arise as secondary effects of abnormalities caused by craniosynostosis, but the main issue is the direct impact on brain growth and development.