Which of the following is NOT associated with critical congenital heart disease?

Marfan syndrome is not directly classified as a critical congenital heart disease. While it is a genetic disorder that can lead to cardiovascular issues, particularly affecting the aorta and causing conditions such as aortic dilation or dissection, it is not itself a congenital heart defect.

In contrast, total anomalous pulmonary venous return, truncus arteriosus, and transposition of the great arteries are all specific types of congenital heart defects that can significantly impact a newborn's circulation and are often life-threatening. These conditions usually require immediate medical attention, including surgical intervention shortly after birth, to correct the altered blood flow and maintain adequate oxygenation.

Understanding the distinction between a genetic syndrome like Marfan syndrome and the specific anatomical anomalies associated with critical congenital heart diseases is crucial for recognizing their implications in neonatal care and treatment strategies.